PROCESS FOR N-ALKYLATING DIHYDRO-LISERGIC ACID

The present invention provides a process for preparingwherein R' is C3-Ce alkyl, -CH2C2-C4 alkenyl, propargyl, C3-C8 cycloalkyl or C1-C6 alkyl substituted C3-C8 cycloalkyl; which comprises: reacting a compound of Formula (II):with a substituted benzenesulfonate of Formula III):wherein R' i...

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Bibliographic Details
Main Author MARZONI,GIFFORD P.,US
Format Patent
LanguageEnglish
Published 28.05.1987
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present invention provides a process for preparingwherein R' is C3-Ce alkyl, -CH2C2-C4 alkenyl, propargyl, C3-C8 cycloalkyl or C1-C6 alkyl substituted C3-C8 cycloalkyl; which comprises: reacting a compound of Formula (II):with a substituted benzenesulfonate of Formula III):wherein R' is as defined above and R2 is hydrogen, bromo, methyl or nitro, in the presence of a base.
Bibliography:Application Number: HU19860004145