PROCESS FOR PREPARING 5-/6-IMIDAZO/1,2-A/PYRIDYL/-PYRIDINE DERIVATIVES

• Main Authors: OGAWA,TOSHIAKI,JP, MIYAKE,KAZUTOSHI,JP, YAMANAKA,MOTOSUKE,JP, OHHARA,HIDETO,JP, SUDA,SHINJI,JP
• Format: Patent
• Language: English
• Published: 30.03.1987
• Edition: 4
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

5-(6-Imidazo[1,2-a]pyridyl)pyridine derivatives represented by general formula: wherein X represents hydrogen atom or methyl group; Y represents cyano group, carboxamido group, hydrogen atom, amino group or a halogen atom; Z represents hydrogen atom or a lower alkyl group; W represents hydrogen atom or a lower alkyl group; R' represents hydrogen atom, a lower alkyl group, phenyl group, a group shown by formula: -CH2R4 in which R4 is a lower alkoxy group, or a group shown by formula:in which R5 and R6 are hydrogen atom or a lower alkyl group; R2 represents hydrogen atom or a halogen atom; and R3 represents hydrogen atom, a lower alkyl group or a halogen atom; or a tautomer thereof; and pharmacologically acceptable salts thereof are disclosed. The 5-(6-imidazo[1,2-a]-pyridyl) pyridine derivatives are effective for treating congestive heart failures.