PROCESS FOR PREPARING 5-/6-IMIDAZO/1,2-A/PYRIDYL/-PYRIDINE DERIVATIVES

5-(6-Imidazo[1,2-a]pyridyl)pyridine derivatives represented by general formula: wherein X represents hydrogen atom or methyl group; Y represents cyano group, carboxamido group, hydrogen atom, amino group or a halogen atom; Z represents hydrogen atom or a lower alkyl group; W represents hydrogen atom...

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Main Authors OGAWA,TOSHIAKI,JP, MIYAKE,KAZUTOSHI,JP, YAMANAKA,MOTOSUKE,JP, OHHARA,HIDETO,JP, SUDA,SHINJI,JP
Format Patent
LanguageEnglish
Published 30.03.1987
Edition4
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:5-(6-Imidazo[1,2-a]pyridyl)pyridine derivatives represented by general formula: wherein X represents hydrogen atom or methyl group; Y represents cyano group, carboxamido group, hydrogen atom, amino group or a halogen atom; Z represents hydrogen atom or a lower alkyl group; W represents hydrogen atom or a lower alkyl group; R' represents hydrogen atom, a lower alkyl group, phenyl group, a group shown by formula: -CH2R4 in which R4 is a lower alkoxy group, or a group shown by formula:in which R5 and R6 are hydrogen atom or a lower alkyl group; R2 represents hydrogen atom or a halogen atom; and R3 represents hydrogen atom, a lower alkyl group or a halogen atom; or a tautomer thereof; and pharmacologically acceptable salts thereof are disclosed. The 5-(6-imidazo[1,2-a]-pyridyl) pyridine derivatives are effective for treating congestive heart failures.
Bibliography:Application Number: HU19860001233