IMPROVED PROCESS FOR PREPARING A-21978 C DERIVATIVES

An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new pr...

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Main Authors HUBER,NEE BRAUN,MARYL.,US, EATON,TOM E.,US, PIEPER,RICHARD,US, HUBER,FLOYD M.,US, ZMIJEWSKI JUN,MILTON J.,US, FORD,LYNDA M.,US, TIETZ,ANTONY J.,US, GODFREY JUN,OTIS W.,US
Format Patent
LanguageEnglish
Published 29.10.1986
Edition4
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Summary:An improved process is provided for producing A-21978C cyclic peptide derivatives having a C2-C14 alkonoyl side chain which comprises feeding a C2-C14 alkanoic acid, or an ester or salt thereof, to the A-21978C-producing culture during the production stages of the fermentation. In addition, a new process is provided for producing the A-21978C antibiotics which comprises cultivating under aerobic conditions a new strain of microorganism.
Bibliography:Application Number: HU19850003912