PROCESS FOR PRODUCTION OF ANTICANCER DAUNOMICINE ANTIBIOTICS AND THIER SALTS
Daunomycin and its salts are prepd. by propagating a strain of the fungus Streptomyces coerulans, pref. the strain deposited at the National Institute for Public Health under no. 00200 in aerobic conditions on culture media contg. assimilable carbon and nitrogen sources, sepg. the produced daunomyci...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
28.08.1985
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | Daunomycin and its salts are prepd. by propagating a strain of the fungus Streptomyces coerulans, pref. the strain deposited at the National Institute for Public Health under no. 00200 in aerobic conditions on culture media contg. assimilable carbon and nitrogen sources, sepg. the produced daunomycin from the fermentation liquor and the accompanying intermediary prods. of the antibiotic biosynthesis, transforming the daunomycin into a pharmaceutically acceptable acid addn. salt and opt. liberating the antibiotic bases. |
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Bibliography: | Application Number: HU19830004394 |