ISOQUNOLINES AS UROKINASE INHIBITORS PROCESS FOR PRODUCING THEM AND USE OF THEM IN THE MANUFACTURE OF A MEDICAMENT

Compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is H and the other is N=C(NH2)2 or NHC(=NH)NH2, and the other substituents are as defined herein, are urokinase (uPA) inhibitors.

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Bibliographic Details
Main Authors FISH PAUL VINCENT FISH PAUL VINCENT, DICKINSON ROGER PETER DICKINSON ROGER PETER, BARBER CHRISTOPHER GORDON BARBER CHRISTOPHER GORDON
Format Patent
LanguageEnglish
Published 28.03.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula (I):and pharmaceutically acceptable salts thereof, wherein one of R1 and R2 is H and the other is N=C(NH2)2 or NHC(=NH)NH2, and the other substituents are as defined herein, are urokinase (uPA) inhibitors.
Bibliography:Application Number: HUP0004491