METHOD OF PREPARING GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

The invention relates to a method of preparing inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lyosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.

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Bibliographic Details
Main Authors SIEGEL, Craig, GIMI, Rayomand, REARDON, Michael, ZHAO, Jin
Format Patent
LanguageEnglish
Hungarian
Published 28.02.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a method of preparing inhibitors of glucosylceramide synthase (GCS) useful for the treatment of metabolic diseases, such as lyosomal storage diseases, either alone or in combination with enzyme replacement therapy, and for the treatment of cancer.
Bibliography:Application Number: HUE19153389