CHEMICAL COMPOUND USEFUL AS INTERMEDIATE FOR PREPARING A CATECHOL-O-METHYLTRANSFERASE INHIBITOR

There is disclosed a methylated intermediate of formula (I) which may be demethylated to provide an inhibitor of catechol-O-methyltransferase useful in the treatment of Parkinson's disease. Also disclosed are methods of making and using said intermediate.

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Bibliographic Details
Main Authors ESZENYI, Tibor, KISS, Laszlo Erno, RUSSO, Domenico, KREIS, Michael, SCHLUMMER, Bjoern, WAHNON, Jorge Bruno Reis, REITER, Klaus, ZIMMERMANN, Axel, LEARMONTH, David Alexander
Format Patent
LanguageEnglish
Hungarian
Published 28.05.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:There is disclosed a methylated intermediate of formula (I) which may be demethylated to provide an inhibitor of catechol-O-methyltransferase useful in the treatment of Parkinson's disease. Also disclosed are methods of making and using said intermediate.
Bibliography:Application Number: HUE12806720