GSK3 INHIBITORS AND METHODS OF USE THEREOF

• Main Authors: HOLSON, Edward, GERMAIN, Andrew, PAN, Jennifer, LEWIS, Michael, NAG, Partha, HAGGARTY, Stephen, BISHOP, Joshua, MUNOZ, Benito, WAGNER, Florence, DANDAPANI, Sivaraman, STEGMAIER, Kimberly, WEIWER, Michel, BANERJI, Versha
• Format: Patent
• Language: English; Hungarian
• Published: 30.09.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides m...