GSK3 INHIBITORS AND METHODS OF USE THEREOF

The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides m...

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Bibliographic Details
Main Authors HOLSON, Edward, GERMAIN, Andrew, PAN, Jennifer, LEWIS, Michael, NAG, Partha, HAGGARTY, Stephen, BISHOP, Joshua, MUNOZ, Benito, WAGNER, Florence, DANDAPANI, Sivaraman, STEGMAIER, Kimberly, WEIWER, Michel, BANERJI, Versha
Format Patent
LanguageEnglish
Hungarian
Published 30.09.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides compounds of formula I, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting kinase (e.g., GSK3 (e.g., GSK3α or GSK3β) or CK1) activity. The present invention further provides methods of using the compounds described herein for treating kinase-mediated disorders, such as neurological diseases, psychiatric disorders, metabolic disorders, and cancer.
Bibliography:Application Number: HUE13780300