Immunoglobulin chimeric monomer-dimer hybrids

The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chai...

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Bibliographic Details
Main Authors Rivera, Daniel S, Peters, Robert T, Mezo, Adam R, Stattel, James M, Low, Susan C, Bitonti, Alan J
Format Patent
LanguageEnglish
Hungarian
Published 28.04.2017
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Summary:The invention relates to a chimeric monomer-dimer hybrid protein wherein said protein comprises a first and a second polypeptide chain, said first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and said second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.
Bibliography:Application Number: HUE10182890