PROCESS FOR THE PREPARATION OF 1-(3,4-DIMETHOXY-PHENYL)-5-ETHYL-7,8-DIMETHOXY-4-METHYL-5H-2,3-BENZODIAZEPINE WITH HIGH PURITY

• Main Authors: CLEMENTIS GYOERGY DR, HAMORI CSABA, SLEGEL PETER DR, JURAK FERENC DR, RUNGE ZSOLT
• Format: Patent
• Language: English
• Published: 28.02.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The present invention relates to the process for the preparation of 1-(3,4-dimethoxy-phenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine of the Formula (I) by reacting 3,4,3',4'-tetramethoxy-6-(a-aceto-propyl)-benzofenon of the general Formula (II) with hydrazine or hydrazine-hydr...