CYCLIC HEXAPEPTIDES

This invention relates to new polypeptide compounds represented by the following formula (I):whereinR1 is as defined in the description and pharmaceutically acceptable salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on beta-1,3-glucan synthas...

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Bibliographic Details
Main Authors TAKASUGI, HISASHI, OHKI, HIDENORI, TOMISHIMA, MASAKI, YAMADA, AKIRA
Format Patent
LanguageEnglish
Published 28.12.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to new polypeptide compounds represented by the following formula (I):whereinR1 is as defined in the description and pharmaceutically acceptable salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on beta-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.
Bibliography:Application Number: HU19980000338