PROCESS FOR PRODUCING N-SUBSTITUTED PHENYL-GLYCINE DERIVATIVES

A process is disclosed for the preparation of a compound of the Formula (VI) (VI) wherein X is a hydrogen atom, or OH, Y is a hydrogen atom, OH or a methyl group, R2 is a CH-COOR group, or a group of the formula (XI) (XI) and R is a C1 to C2 alkyl group, which comprises the step of: reacting a conde...

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Main Authors KRUPPA,MARTA,HU, HUSZAR,CSABA,HU, SOMFAI,EVA,HU, PALI,LAJOSNE,HU, BAN,KAROLY,HU, BAN,ANNAMARIA,HU
Format Patent
LanguageEnglish
Published 29.03.1993
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process is disclosed for the preparation of a compound of the Formula (VI) (VI) wherein X is a hydrogen atom, or OH, Y is a hydrogen atom, OH or a methyl group, R2 is a CH-COOR group, or a group of the formula (XI) (XI) and R is a C1 to C2 alkyl group, which comprises the step of: reacting a condensed salt of the Formula (IV) (IV) wherein Me is Na+ or K+, with a reactive derivative of trifluoromethane-sulfonic acid of the Formula (V) F3C-SO2OH. The compounds of the Formula (VI) are intermediates in the preparation of penicillins and cephalosporins with antibiotic activity.
Bibliography:Application Number: HU19890003818