PROCESS FOR PRODUCING 4-CHLORO-3-SULFAMOYLBENZOIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represen...

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Main Authors VIRAG,SANDOR,HU, MARMAROSI,TAMASNE,HU, SIMON,GYOERGY,HU, PALOSI,ENDRE,HU, KORBONITS,DEZSOE,HU, SZVOBODA,GYOERGYNE,HU, HARSING,LASZLO,HU, MOLNAR,LEVENTENE,HU, GERGELY,VERA,HU
Format Patent
LanguageEnglish
Published 01.03.1993
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The novel compounds according to the invention correspond to the general formula I in which R represents hydrogen, a trifluoromethyl or carboxyl group, an alkoxycarbonyl group having 2-5 carbon atoms, a cyano, benzoyl or sulphamoyl group or an alkylsulphonyl group having 1-4 carbon atoms, R represents hydrogen, an alkylthio or alkylsulphonyl group each having 1-4 carbon atoms, a straight or branched alkyl group having 1-4 carbon atoms, or a benzylthio, benzylsulphonyl, phenyl, hydroxyl or thiol group and R represents hydrogen or chlorine. The novel compounds act as diuretics and saluretics and have a hypotensive action.
Bibliography:Application Number: HU19870006131