PROCESS FOR THE PRODUCTION OF A TABLE CRYSTALLIZING IN THE MONOCLINIC SYSTEM, WHICH CONTAINS LIGHT-, HEAT-, AND MOISTURE- SENSITIVE ACTIVE AGENTS

PCT No. PCT/HU91/00039 Sec. 371 Date Jun. 5, 1992 Sec. 102(e) Date Jun. 5, 1992 PCT Filed Aug. 23, 1991 PCT Pub. No. WO92/03126 PCT Pub. Date Mar. 5, 1992.The invention relates to a process for the preparation of a tablet or dragée composition containing a moisture-, heat- and light-sensitive compou...

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Main Authors LANGO,JOZSEF,HU, SZILAGYI,JUDIT,HU, ORBAN,ERNOE,HU, BACSA,GYOERGY,HU, SZENDREI,LEVENTE,HU, BOBAK,TAMASNE,HU, MAROSSY,KATALIN,HU, TABINE SIMO,MARGIT,HU, MATHE,TIBOR,HU, BIDLO,GABORNE,HU, FEKETENE BEKE,KATALIN,HU, KOVACS,ISTVAN,HU, JANCSO,SANDOR,HU
Format Patent
LanguageEnglish
Published 28.01.1993
Edition5
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Summary:PCT No. PCT/HU91/00039 Sec. 371 Date Jun. 5, 1992 Sec. 102(e) Date Jun. 5, 1992 PCT Filed Aug. 23, 1991 PCT Pub. No. WO92/03126 PCT Pub. Date Mar. 5, 1992.The invention relates to a process for the preparation of a tablet or dragée composition containing a moisture-, heat- and light-sensitive compounds having monoclinic crystalline structure as active ingredients, which comprises homogenizing the active ingredient with 0.2 to 1.5 parts by weight of an anhydrous alkaline earth metal salt and 0.5 to 2.5 parts by weight of microcrystalline cellulose calculated for the active ingredient and optionally with one or more pharmaceutically acceptable carrier(s) and/or additive(s) and compressing the homogeneous mixture obtained to tablets in a manner known per se and, if desired, coating the tablet thus obtained in a manner known per se.
Bibliography:Application Number: HU19900005314