PROCESS FOR PRODUCING STABLE NICORANDYL COMPOSITIONS

A method for producing a stable preparation contain­ing nicorandil, a saturated higher aliphatic acid or a saturated higher alcohol which is solid at ordinary tempera­tures, and optionally, an organic acid such as fumaric acid, oxalic acid, salicylic acid, tartaric acid or glutaric acid is disclosed...

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Bibliographic Details
Main Authors IIDA,YOSHIMITSU,JP, SUMIDA,SHUJI,JP
Format Patent
LanguageEnglish
Published 30.01.1989
Edition4
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A method for producing a stable preparation contain­ing nicorandil, a saturated higher aliphatic acid or a saturated higher alcohol which is solid at ordinary tempera­tures, and optionally, an organic acid such as fumaric acid, oxalic acid, salicylic acid, tartaric acid or glutaric acid is disclosed.Nicorandil is useful as a curative for various types of angina pectoris. However, it is unstable in humid condi­tions and under the compressive pressure exerted by punching operations in tablets making and, therefore, the development of a stable nicorandil preparation has been desired.
Bibliography:Application Number: HU19870000123