PROCESS FOR THE EXTRACTION OF NUCLEINIC ACIDS AND PURINE BASES FROM GELATINE

The invention relates to a process for removing nucleic acids and purine bases from gelatine by (a) adding cyclodextrin bead polymer having a particle size of 20 to 600 mu , a cyclodextrin content of 30 to 70% and a polyvinyl alcohol content of 0.3 to 0.5% to the gelatin solution in a weight ratio o...

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Bibliographic Details
Main Authors FENYVES,EVA,HU, SZUECS,MIKLOS,HU, PALOTAS,ISTVANNE,HU, SZEJTLI,JOZSEF,HU
Format Patent
LanguageEnglish
Published 29.06.1987
Edition4
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Summary:The invention relates to a process for removing nucleic acids and purine bases from gelatine by (a) adding cyclodextrin bead polymer having a particle size of 20 to 600 mu , a cyclodextrin content of 30 to 70% and a polyvinyl alcohol content of 0.3 to 0.5% to the gelatin solution in a weight ratio of 1:1 to 10:1 calculated on the amount of the gelatin then filtering off the cyclodextrin polymer or (b) passing the gelatin solution through a cyclodextrin bead polymer column, whereby the amount of the gelatin is 5 to 50% of the weight of the column charge, then eluting the nucleic acids and the purine bases from the cyclodextrin bead polymer.
Bibliography:Application Number: HU19840004730