IMPROVED PROCESS FOR PRODUCING COMPOSITION CONTAINING COAGULATING FAKTOR VIII FROM UNDERCOOLED HUMAN BLOOD PLASKA

An antihemophilic factor preparation (AHF) of high solubility and long half-life is produced in high yields by complete or partial thawing of deep-frozen human blood plasma by irradiation with electromagnetic waves of a frequency of about 108-1015 for a period of time and with an energy penetration...

Full description

Saved in:
Bibliographic Details
Main Authors HANSEN,JO/RGEN,F.,DK, RASMUSSEN,MIRELLA,E.,DK, JENNSEN,JO/RGEN V.,DK
Format Patent
LanguageEnglish
Published 30.05.1983
Subjects
BASIC ELECTRIC ELEMENTS
CHEMISTRY
CURRENT COLLECTORS
ELECTRICITY
HUMAN NECESSITIES
HYGIENE
LINE CONNECTORS
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:An antihemophilic factor preparation (AHF) of high solubility and long half-life is produced in high yields by complete or partial thawing of deep-frozen human blood plasma by irradiation with electromagnetic waves of a frequency of about 108-1015 for a period of time and with an energy penetration such that the temperature in the thawed plasma does not exceed 10 DEG C. at any point, and processing in a manner known per se by centrifuging the thawed product to form a cryoprecipitate, redissolving the cryoprecipitate in a buffer and isolating a concentrated solution which, if desired, is freeze-dried. Irradiation is preferably effected by microwaves of a frequency of 108-3x1011 Hz, in particular 2x109-3x1010 Hz, or by infrared light, said frozen plasma being preheated if desired. The preparation is suitable for injection performed by the patient himself without medical assistance.
Bibliography:Application Number: HU1979NO00237