6-MEMBERED N-HETEROARYLOXAZOLIDINONES

Nitrogen-contg. heteroaryl-oxazolidinones of formula (I) and their salts and N-oxides are new. R = N3, OH, OR2, OSO2R or NR R ; R = 1-8C acyl or OH protecting gp.; R = 1-4C alkyl or phenyl opt. substd. by 1-4C alkyl; R , R = H, 3-6C cycloalkyl, phenyl, 1-8C alkyl or NH2 protecting gp.; or R or R = C...

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Main Authors HANNO WILD, BERND RIEDL, KLAUS SCHALLER, HANS-OTTO WERLING, ANDREAS STOLLE, DIETER HAEBICH, HARALD LABISCHINSKI, KLAUS DIETER BREMM, HEIN-PETER KROLL, REINER ENDERMANN
Format Patent
LanguageEnglish
Published 30.04.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Nitrogen-contg. heteroaryl-oxazolidinones of formula (I) and their salts and N-oxides are new. R = N3, OH, OR2, OSO2R or NR R ; R = 1-8C acyl or OH protecting gp.; R = 1-4C alkyl or phenyl opt. substd. by 1-4C alkyl; R , R = H, 3-6C cycloalkyl, phenyl, 1-8C alkyl or NH2 protecting gp.; or R or R = COR ; R = H, 3-6C cycloalkyl, phenyl or 1-8C alkyl; D = (a) 6-membered C-bonded aromatic heterocycle contg. at least 1 N atom; (b) C-bonded bi- or tricyclic aromatic gp. with 6-membered rings of which at least 1 is N-contg, etc.
Bibliography:Application Number: HR1995P000408