KRAS G12C INHIBITORS

The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

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Bibliographic Details
Main Authors Burgess, Laurence E, Blake, James F, Fischer, John P, Tang, Tony Pisal, Marx, Matthew Arnold, Savechenkov, Pavel, Mejia, Macedonio J, Vigers, Guy P.A, Rodriguez, Martha E, Christensen, James Gail, Smith, Christopher Ronald, Chicarelli, Mark Joseph, Cook, Adam, Fell, Jay Bradford
Format Patent
LanguageCroatian
English
Published 23.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.
Bibliography:Application Number: HR2023P000377T