INHIBITORS OF THE MENIN-MLL INTERACTION

The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

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Bibliographic Details
Main Authors Claremon, David A, Zheng, Yajun, Marcus, Andrew, Yuan, Jing, Cacatian, Salvacion, Singh, Suresh B, Morales-Ramos, Angel, Venkatraman, Shankar, Houston, Travis L, Parent, Stephan D, Dong, Chengguo, Dillard, Lawrence, Wayne, Lotesta, Stephen D, Zhuang, Linghang, Jia, Lanqi, Fan, Yi
Format Patent
LanguageCroatian
English
Published 19.02.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.
Bibliography:Application Number: HR2020P001771T