ANTI-FERROPORTIN 1 MONOCLONAL ANTIBODIES AND USES THEREOF

Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte coun...

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Bibliographic Details
Main Authors Leung, Donmienne Doen Mun, Witcher, Derrick Ryan, Luan, Peng, Tang, Ying, Manetta, Joseph Vincent
Format Patent
LanguageCroatian
English
Published 22.04.2016
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Summary:Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of human FPN1, and which are effective in maintaining or increasing the transport of iron out of mammalian cells and/or maintaining or increasing the level of serum iron, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a subject in vivo.
Bibliography:Application Number: HR2016P000302T