PROCESS FOR THE PREPARATION OF [(1R), 2S]-2-AMINOPROPIONIC ACID 2-[4-(4-FLUORO-2-METHYL-1H-INDOL-5-YLOXY)-5-METHYLPYRROLO]2,1-f-[1,2,4-TRIAZIN-6-YLOXY]-1-METHYLETHYL ESTER

The invention relates to an improved process for preparing [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.

Saved in:
Bibliographic Details
Main Authors LAPORTE, THOMAS L, LEAHY, DAVID K, MUSLEHIDDINOGLU, JALE, LAI, CHIAJEN, CRISPINO, GERARD A, LOBBEN, PAUL C, DISCORDIA, ROBERT P, PESTI, JAAN A, HAMEDI, MOURAD, THORNTON, JOHN E, XU, ZHONGMIN, SPANGLER, LORI ANN
Format Patent
LanguageCroatian
English
Published 31.03.2013
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The invention relates to an improved process for preparing [(1R), 2S]-2-aminopropionic acid 2-[4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]-1-methylethyl ester of the formula: Compound I has been shown to be useful for the treatment of certain types of cancer.
Bibliography:Application Number: HR2013P000099T