AZETIDINES AS MEK INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES

• Main Authors: JOERG BUSSENIUS, JEAN-CLAIRE LIMUN MANALO, CHARLES M. BLAZEY, NEEL KUMAR ANAND, JEFFRY KIMO CURTIS, SIMONA COSTANZO, ELENA KOLTUN, OWEN JOSEPH BOWLES, TSZE H. TSANG, ANGIE INYOUNG KIM, LARISA DUBENKO, CSABA J. PETO, ABIGAIL R. KENNEDY, NAING AAY, STEVEN CHARLES DEFINA, ANAGHA ABHIJIT JOSHI, KENNETH D. RICE
• Format: Patent
• Language: Croatian; English
• Published: 31.08.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Spoj formule I: ili pojedinačni stereoizomer ili smjesa stereoizomera, ili po izboru njegova farmaceutski prihvatljiva sol ili solvat, naznačen time što su A, X, R1, R2, R3, R4, R5, R6 i R7 kako je definirano za grupu A, grupu B, grupu C ili grupu D: Grupa A: A je arilen po izboru supstituiran s jed...