PROCESS FOR THE PREPARATION OF 3-SPIRO'CYCLOHEXAM-1,3'-'3H ^INDOLIN-2'-ONE^ DERIVATIVES

The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) characterized by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presenc...

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Main Authors GERGELY HEJA, LAJOS NAGY, ANDREA SANTANE CSUTOR, ISTVAN HERMECZ, FELIX HAJDU, TIBORNE SZOMOR, EVA CSIKOS, CSILLA MAJLATH, GYOERGYNE SZVOBODA, GERGELYNE HEJA, CSABA GONCZI
Format Patent
LanguageEnglish
Published 30.06.2005
Edition7
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Summary:The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) characterized by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presence of a phase transfer catalyst, reacting with a.) an aqeuos solution of a base, or b.) a base in solid form directly and if desired transforming the compound of formula (I) thus obtained into its salt.
Bibliography:Application Number: HR2004P000200