8-alkoxyquinolonecarboxylic acid and salts thereof excellent in the selective toxicity and process of preparing the same
Quinolonecarboxylic acid derivatives of the following formula: wherein R indicates a hydrogen atom or lower alkyl group, R1 indicates a lower alkyl group, R2 indicates a hydrogen atom, amino group or nitro group, X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylp...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
20.06.1997
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | Quinolonecarboxylic acid derivatives of the following formula: wherein R indicates a hydrogen atom or lower alkyl group, R1 indicates a lower alkyl group, R2 indicates a hydrogen atom, amino group or nitro group, X indicates a halogen atom, and Z indicates a halogen atom, piperazino group, N-methylpiperazino group, 3-methylpiperazino group, 3-hydroxypyrrolidino group, or pyrrolidino group of the following formula, (here, n is 0 or 1, R3 indicates a hydrogen atom or lower alkyl group, R4 indicates a hydrogen atom, lower alkyl group and R5 indicates a hydrogen atom, lower alkyl group, acyl group or alkoxycarbonyl group), the hydrates and pharmaceutically acceptable salts thereof are useful as antibacterial agents. |
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Bibliography: | Application Number: HK19970000797 |