SUPPRESSION OF CANCERS

The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth...

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Bibliographic Details
Main Authors MARKS, Philip, LECANE, Phil, MADEC, Frederic, FOSTER, Keith
Format Patent
LanguageChinese
English
Published 14.09.2018
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Summary:The present invention relates to a method for suppressing or treating cancer, in particular to a method for suppressing or treating one or more of colorectal cancer, breast cancer, prostate cancer and/ or lung cancer. The therapy employs use of a non-cytotoxic protease, which is targeted to a growth hormone-secreting cell such as to a pituitary cell. When so delivered, the protease is internalised and inhibits secretion/ transmission of growth hormone from said cell. The present invention also relates to polypeptides and nucleic acids for use in said methods.
Bibliography:Application Number: HK20180106227