A METHOD FOR DETERMINING THE PROPENSITY FOR CALCIFICATION

The present invention relates to a method for determining the propensity of a fluid for calcification characterized by the following steps: (i) adding a soluble calcium salt and a soluble phosphate salt to a sample of said fluid; (ii) incubating said sample at conditions allowing the formation of ca...

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Bibliographic Details
Main Authors STEFAN FARESE, STEFFEN GRBER, ANDREAS PASCH, WILHELM JAHNEN-DECHENT
Format Patent
LanguageChinese
English
Published 25.09.2015
Subjects
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Summary:The present invention relates to a method for determining the propensity of a fluid for calcification characterized by the following steps: (i) adding a soluble calcium salt and a soluble phosphate salt to a sample of said fluid; (ii) incubating said sample at conditions allowing the formation of calciprotein particles (CPPs); and (iii) determining one or more of the following: (a) the rate of the formation of primary and/or secondary CPPs; (b) the amount of primary and/or secondary CPPs; and/or (c) the rate of the transition of primary CPPs into secondary CPPs, wherein an increase in one or more of (a), (b) and/or (c) of step (iii) indicates an increased propensity of said fluid for calcification.
Bibliography:Application Number: HK20150102738