DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST

A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obe...

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Bibliographic Details
Main Authors QUIMBY, STEVEN JAMES, HOLLOWAY, WILLIAM GLEN, SMITH, DANA RAE, MATT, JAMES EDWARD JUNIOR, DE LA TORRE, MARTA GARCIA, FRITZ, JAMES ERWIN, MITCH, CHARLES HOWARD, SIEGEL, MILES GOODMAN, STUCKY, RUSSELL DEAN, PEDREGAL-TERCERO, CONCEPCION, DIAZ BUEZO, NURIA, TAKEUCHI, KUMIKO, THOMAS, ELIZABETH MARIE, CHAPPELL, MARK DONALD, BLANCO-PILLADO, MARIA-JESUS, WOLFE, CHAD NOLAN
Format Patent
LanguageEnglish
Published 03.12.2010
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A compound of the formula (I) wherein the variables X 1 to X 10 , R 1 to R 7 including R 3' , E, v, y, z, A and B are as described, or a pharmaceutically acceptable salt, solvate, enantiomer, racemate, diastereomer or mixtures thereof, useful for the treatment, prevention or amelioration of obesity and Related Diseases is disclosed.
Bibliography:Application Number: HK20100108780