TERPHENYL DERIVATIVES FOR TREATMENT OF ALZHEIMER'S DISEASE

The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R 1 -R 4 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation...

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Main Authors READER, VALERIE, WILSON, FRANCIS, MAJOR, JEREMY, SMELT, KATHRYN, BOUSSARD, CYRILLE, TAYLOR, JESS, BURCKHARDT, SVENJA, ZHANG, YAN, LEFORMAL, ADELINE, HERNADEZ-PERNI, REMEDIOS, REID, ALISON, HO, CHIH YUNG, SUNOSE, MIHIRO, HARRISON, RICHARD, JOHN, CANSFIELD, ANDREW
Format Patent
LanguageEnglish
Published 20.05.2010
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to compounds having the general formula (I) with the definitions of X, Y, R 1 -R 4 given below, and/or a salt or ester thereof. Furthermore the invention relates to the use of said compounds for the treatment of Alzheimer's disease and their use for the modulation of ³-secretase activity.
Bibliography:Application Number: HK20090112111