SUBSTITUTED ESTRATRIEN DERIVATIVES AS 17BETA HSD INHIBITORS 17HSD

This invention relates to novel substituted estratrien derivatives of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder requiring the inhibition of a 17ß-hydroxysteroid dehydrogenase (17- HSD) type 1, type 2 and/or ty...

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Main Authors HUSEN, BETTINA B, SCHOEN, UWE U, MESSINGER, JOSEF J, THOLE, HEINRICH-HUBERT H-H, KOSKIMIES, PASI P, UNKILA, MIKKO M
Format Patent
LanguageChinese
English
Published 10.07.2015
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STEROIDS
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Summary:This invention relates to novel substituted estratrien derivatives of general formula (I) useful in therapy, especially for use in the treatment and/or prevention of a steroid hormone dependent disorder requiring the inhibition of a 17ß-hydroxysteroid dehydrogenase (17- HSD) type 1, type 2 and/or type 3 enzyme, as well as to their salts, to pharmaceutical preparations containing these compounds and to processes for the preparation of these compounds.
Bibliography:Application Number: HK20100100621