Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus

Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-en...

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Bibliographic Details
Main Authors RODERICK JACK RAY, DANIEL ELMONT DOBRY, DANA MARIE SETTELL, KENNY RAY SPENCE, HEATHER LYNN MELCHER DEIBELE, RONALD ARTHUR BEYERINCK
Format Patent
LanguageEnglish
Published 04.11.2005
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Conventional spray-drying methods are improved by incorporation of a pressure nozzle and a diffuser plate to improve the flow of drying gas and a drying chamber extension to increase drying time, such improvements leading to the formation of homogeneous solid dispersions of drugs in concentration-enhancing polymers.
Bibliography:Application Number: HK20050106592