USE OF BIODEGRADABLE MICROSPHERES WHICH RELEASE AN ANTICANCER AGENT, FOR TREATING GLIOBLASMA
The use of biodegradable microspheres that liberate a radiosensitive anticancer agent at the site of surgery to remove glioblastoma, these being used in conjunction with radiotherapy, is new. The use of biodegradable microspheres that liberate a radiosensitive anticancer agent at the site of surgery...
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Main Authors | , , |
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Format | Patent |
Language | Chinese English |
Published |
23.12.2005
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Subjects | |
Online Access | Get full text |
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Summary: | The use of biodegradable microspheres that liberate a radiosensitive anticancer agent at the site of surgery to remove glioblastoma, these being used in conjunction with radiotherapy, is new. The use of biodegradable microspheres that liberate a radiosensitive anticancer agent at the site of surgery to remove glioblastoma, these being used in conjunction with radiotherapy. The microspheres containing the anticancer agent are coated with a polymer that delays and prolongs the liberation of the active material, and are inserted into the area of the excision at least every square cm to a depth of 2 - 3 cm so as to maintain a therapeutically-effective concentration in the parenchymal space whilst radiotherapy is carried out, increasing the patient's survival time by at least 90 weeks. The microspheres are administered in a suspension containing 1 - 1.5 % (weight/volume) of a viscous agent, 0.5 - 1.5 % of a surfactant, and 3.5 - 4.5 % of an isotonic agent. |
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Bibliography: | Application Number: HK20020108661 |