MIMÉTICOS DE APELINA SINTÉTICOS PARA EL TRATAMIENTO DE INSUFICIENCIA CARDIACA

• Main Authors: GOLOSOV ANDREI, YASOSHIMA KAYO, HU QI-YING, ZHAO HONGJUAN, GROSCHE PHILIPP, ZECRI FRÉDÉRIC, PARKER DAVID THOMAS, IMASE HIDETOMO
• Format: Patent
• Language: Spanish
• Published: 15.10.2015
• Subjects: CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES

LA PRESENTE INVENCIÓN SE REFIERE A COMPOSICIONES NOVEDOSAS QUE COMPRENDEN SECUENCIAS DE PÉPTIDOS Y POLIPÉPTIDOS MODIFICADAS DISEÑADAS PARA TRATAR ENFERMEDADES CARDIOVASCULARES EN LOS SUJETOS A QUIENES SE ADMINISTREN, Y LAS CUALES EXHIBEN UNA MAYOR RESISTENCIA A LA DEGRADACIÓN, Y UNA BIOACTIVIDAD EQUIVALENTE O MAYOR QUE SUS CONTRA-PARTES DE TIPO SILVESTRE. LA INVENCIÓN TAMBIÉN SE REFIERE A MÉTODS PARA LA ELABORACIÓN DE ESTAS COMPOSICIONES, Y AL USO DE ESTAS COMPOSICIONES COMO AGENTES FARMACÉUTICAMENTE ACTIVOS PARA TRATAR ENFERMEDADES CARDIOVASCULARES A pressure support system that comprises a patient circuit, a docking assembly, and a tank. The patient circuit delivers a pressurized flow of breathable gas to a patient. The docking assembly has an inlet and an outlet that is adapted to receive the pressurized flow of breathable gas, and is also adapted to be connected with the patient circuit. The tank is constructed and arranged to be removably connected with the docking assembly, and enables the pressurized flow of breathable gas to pass therethrough. The tank is also adapted to contain a liquid such that a humidity level of the pressurized flow of breathable gas is elevated as the pressurized flow of breathable gas passes therethrough.