COMPUESTOS DE QUINOLINA Y QUINOXALINA
LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA GENERAL I EN LA QUE R1,R2,R3,R4,R5,R6,R7,J, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON INHIBIDORES DE LA HMG COA REDUCTASA POR LO QUE SON DE UTILIDAD EN CUADROS TALES DISLIPIDEMIA, HIPERBETALIPOPROTEINEMIA, HIPERCO...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | Spanish |
Published |
02.03.2005
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Edition | 6 |
Subjects | |
Online Access | Get full text |
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Summary: | LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE FORMULA GENERAL I EN LA QUE R1,R2,R3,R4,R5,R6,R7,J, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SON INHIBIDORES DE LA HMG COA REDUCTASA POR LO QUE SON DE UTILIDAD EN CUADROS TALES DISLIPIDEMIA, HIPERBETALIPOPROTEINEMIA, HIPERCOLESTEROLEMIA, ENTRE OTROS MENCIONADOS EN LA SOLICITUD.
Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans. |
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Bibliography: | Application Number: GT20040000050 |