GR77312

Compounds of the formula wherein Ar is R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is =CO, =CH-CN, =CH-OH, -O-, -S-, -NH-, +TR and R is hydrogen, 4-fluoro, 4-chloro, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chloro, 4-methyl or 4-methoxy; and non-toxic, pharmacologically...

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Main Authors DR HERBERT MERZ, DR RUDOLF BAUER, DR JOACHIM MIERAU, DR ADOLF LANGBEIN, DR HANS MICHAEL JENNEWEIN, DR RAINER SOBOTTA
Format Patent
LanguageEnglish
Published 11.09.1984
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula wherein Ar is R1 is hydrogen, fluorine, bromine, methyl or methoxy; X is =CO, =CH-CN, =CH-OH, -O-, -S-, -NH-, +TR and R is hydrogen, 4-fluoro, 4-chloro, 4-trifluoromethyl, 3-trifluoromethyl, 3-trifluoromethyl-4-chloro, 4-methyl or 4-methoxy; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as neuroleptics.
Bibliography:Application Number: GR19810166672