GR75489

A process for preparing 2-[2-[(2-furylmethyl)thio]ethylamino]-5-[(6-methyl-3-pyridinyl)methyl] -4(1H)-Y# pyrimidinone by reacting a guanidine and a 2-formyl-3-(6-methyl-3-pyridinyl)propionate ester. The pyrimidinone product is particularly useful as an intermediate for a 5-dimethylaminomethylfuryl c...

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Bibliographic Details
Main Authors W.L.MENDELSON, C.S.LABAW, ALAN W. TREMPER
Format Patent
LanguageEnglish
Published 23.07.1984
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for preparing 2-[2-[(2-furylmethyl)thio]ethylamino]-5-[(6-methyl-3-pyridinyl)methyl] -4(1H)-Y# pyrimidinone by reacting a guanidine and a 2-formyl-3-(6-methyl-3-pyridinyl)propionate ester. The pyrimidinone product is particularly useful as an intermediate for a 5-dimethylaminomethylfuryl compound having histamine H2- antagonist activity.
Bibliography:Application Number: GR19820168255