Substituted mono- and bipyridylmethylpyridone as angiotensine II antagonists

• Main Authors: HANKO, RUDOLF, MUELLER, ULRICH, STASCH, JOHANNES-PETER, KAZDA, STANISLAV, DR, MUELLER-GLIEMANN, MATTHIAS, ZAISS, SIEGFRIED, FEY, PETER, KRAEMER, THOMAS, BEUCK, MARTIN, WOHLFEIL, STEFAN, KNORR, ANDREAS, BISCHOFF, HILMAR, DENZER, DIRK, DRESSEL, JUERGEN, HUEBSCH, WALTER
• Format: Patent
• Language: English
• Published: 28.11.1997
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as ac...