Substituted mono- and bipyridylmethylpyridone as angiotensine II antagonists

Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as ac...

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Main Authors HANKO, RUDOLF, MUELLER, ULRICH, STASCH, JOHANNES-PETER, KAZDA, STANISLAV, DR, MUELLER-GLIEMANN, MATTHIAS, ZAISS, SIEGFRIED, FEY, PETER, KRAEMER, THOMAS, BEUCK, MARTIN, WOHLFEIL, STEFAN, KNORR, ANDREAS, BISCHOFF, HILMAR, DENZER, DIRK, DRESSEL, JUERGEN, HUEBSCH, WALTER
Format Patent
LanguageEnglish
Published 28.11.1997
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Substituted mono- and bipyridylmethylpyridones are prepared either by reaction of pyridones with mono- or bipyridylmethylhalogen compounds or by reaction of pyridone-substituted halopyridines with tetrazolylphenylboronic acids. The substituted mono- and bipyridylmethylpyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.
Bibliography:Application Number: GR19970402103T