Compounds for use in the treatment of diseases and conditions associated with inflammation or autoimmunity

4-(6-oxo-2-(trifluoromethyl)-3,6-dichromeno[7,8-d]imidazole-8-yl)benzonitrile, also known as CF3CN, for use in the treatment of diseases or conditions associated with inflammation or autoimmunity, is provided. CF3CN is preferably administered with one or more pharmaceutically acceptable excipients....

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Bibliographic Details
Main Authors Man-Ling Ho, Alleyn Thomas Plowright, Thomas Pfeiffer
Format Patent
LanguageEnglish
Published 29.05.2024
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:4-(6-oxo-2-(trifluoromethyl)-3,6-dichromeno[7,8-d]imidazole-8-yl)benzonitrile, also known as CF3CN, for use in the treatment of diseases or conditions associated with inflammation or autoimmunity, is provided. CF3CN is preferably administered with one or more pharmaceutically acceptable excipients. The diseases or conditions associated with inflammation or autoimmunity are as herein defined. The neuroprotective effect of CF3CN on damage induced by LPS on culture of mesencephalic neurons is exemplified. CF3CN may be administered as a single or multiple daily doses wherein the dose comprises at least 0.001mg of CF3CN. CF3CN may be administered with one or more additional drug products.
Bibliography:Application Number: GB20220017453