Anti-TCR antibody molecules and uses thereof
The disclosure provides methods of expanding T cells ex vivo comprising contacting the T cells with antibody molecules that bind to TCR Vβ regions. In some embodiments, the T cells comprise one or more nucleic acid molecule encoding an exogenous cellular receptor, for example, a chimeric antigen rec...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
15.12.2021
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Subjects | |
Online Access | Get full text |
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Summary: | The disclosure provides methods of expanding T cells ex vivo comprising contacting the T cells with antibody molecules that bind to TCR Vβ regions. In some embodiments, the T cells comprise one or more nucleic acid molecule encoding an exogenous cellular receptor, for example, a chimeric antigen receptor (CAR) or an exogenous T cell receptor (TCR). |
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Bibliography: | Application Number: GB202109794 |