Organomimetic devices and methods of use and manufacturing thereof

A method of making a porous membrane for a microfluidic device. The microfluidic device can be used to culture cells in its microfluidic channels and can be included in an organomimetic device. The organomimetic device can be part of dynamic system that can apply mechanical forces to the cells by mo...

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Bibliographic Details
Main Authors Daniel Levner, Kambez Hajipouran Benam, Georg Bauer, Thomas Umundum, Norman Wen, Richard Novak, Geraldine A Hamilton, II Guy Thompson, Christopher David Hinojosa, Donald E Ingber, Karel Domansky, Jose Fernandez-Alcon, Remi Villenave, Alfred Paris
Format Patent
LanguageEnglish
Published 24.03.2021
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SPIRITS
TRANSPORTING
VINEGAR
WINE
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Summary:A method of making a porous membrane for a microfluidic device. The microfluidic device can be used to culture cells in its microfluidic channels and can be included in an organomimetic device. The organomimetic device can be part of dynamic system that can apply mechanical forces to the cells by modulating the microfluidic device and the flow of fluid through the microfluidic channels. The membrane in the organomimetic device can be modulated mechanically via pneumatic means and/or mechanical means. The organomimetic device can be manufactured by the fabrication of individual components separately, for example, as individual layers that can be subsequently laminated together.
Bibliography:Application Number: GB20200011499