1-Acetic acid indole derivatives with PGD2 activity

Compounds of general formula II wherein Wis chloro of fluoro R1is an optionally substituted aryl R4is H or optionally substituted alkyl The compounds may be used in the treatment of asthma, allergic rhinitis and other inflammatory diseases mediated by prostaglandin D2 (PGD2) or other agonists acting...

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Bibliographic Details
Main Authors RICHARD EDWARD ARMER, GRAHAM MICHAEL WYNNE
Format Patent
LanguageEnglish
Published 05.08.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of general formula II wherein Wis chloro of fluoro R1is an optionally substituted aryl R4is H or optionally substituted alkyl The compounds may be used in the treatment of asthma, allergic rhinitis and other inflammatory diseases mediated by prostaglandin D2 (PGD2) or other agonists acting on the CRTH2 receptor.
Bibliography:Application Number: GB20080001674