Suspensions of water-swellable polymer particles which are substantially water-free or contain insufficient water to fully swell the particles

A liquid composition for adherence to a surface, notably to a bodily surface, especially a mucosal surface, comprises water-swellable polymer particles suspended in a liquid diluent, wherein the liquid diluent is substantially free of water or includes an amount of water insufficient to fully swell...

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Bibliographic Details
Main Authors IAN GORDON JOLLIFFE, JONATHAN CRAIG RICHARDSON, FRANK CHADWICK HAMPSON, COLIN DAVID MELIA, PETER WILLIAM DETTMAR
Format Patent
LanguageEnglish
Published 25.08.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A liquid composition for adherence to a surface, notably to a bodily surface, especially a mucosal surface, comprises water-swellable polymer particles suspended in a liquid diluent, wherein the liquid diluent is substantially free of water or includes an amount of water insufficient to fully swell the polymer particles. On admixture with water the composition thickens and becomes more adherent to surfaces. Thus the composition may be easy to administer but may become thick and adherent at the treatment site. The polymer particles may not comprise a mixture of anionic and cationic polymers. Preferred polymer particles are alginate particles and preferred diluents are glycerol, propylene glycol and polyethylene glycol or mixtures thereof. The compositions may be used to treat or prevent damage to or inflammation of a bodily surface.
Bibliography:Application Number: GB20030003831