The use of staurosporine analogues for enhancing neurotrophin activity

The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of neuronal degeneration such as Alzheimer's, Huntington's corea, epilepsy, and brain or spinal cord injuries. The compounds are believed...

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Main Authors HOWARD BARFF BROUGHTON, SCOTT JEFFREY POLLACK, SARAH JANE HARPER
Format Patent
LanguageEnglish
Published 01.12.1999
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of neuronal degeneration such as Alzheimer's, Huntington's corea, epilepsy, and brain or spinal cord injuries. The compounds are believed to potertrate neurotrophin-3 (NT-3) action without unhibiting tyrosine kinase (Trk).
AbstractList The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of neuronal degeneration such as Alzheimer's, Huntington's corea, epilepsy, and brain or spinal cord injuries. The compounds are believed to potertrate neurotrophin-3 (NT-3) action without unhibiting tyrosine kinase (Trk).
Author HOWARD BARFF BROUGHTON
SCOTT JEFFREY POLLACK
SARAH JANE HARPER
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Snippet The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of...
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MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title The use of staurosporine analogues for enhancing neurotrophin activity
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