The use of staurosporine analogues for enhancing neurotrophin activity

The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of neuronal degeneration such as Alzheimer's, Huntington's corea, epilepsy, and brain or spinal cord injuries. The compounds are believed...

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Bibliographic Details
Main Authors HOWARD BARFF BROUGHTON, SCOTT JEFFREY POLLACK, SARAH JANE HARPER
Format Patent
LanguageEnglish
Published 01.12.1999
Edition6
Subjects
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Summary:The staurosporine analogues BE-13793C, a monosaccharide derivative thereof, rebeccamycin and NB-506 are indicated for new therapeutic uses in conditions of neuronal degeneration such as Alzheimer's, Huntington's corea, epilepsy, and brain or spinal cord injuries. The compounds are believed to potertrate neurotrophin-3 (NT-3) action without unhibiting tyrosine kinase (Trk).
Bibliography:Application Number: GB19990012318