Cofactor for transmethylation

5'-Methylthioadenosine nucleosidase is used as a cofactor for carminomycin 4-O-methyltransferase. The system may be used to convert carminomycin, especially when present as a contaminant in daunorubicin solution, into daunorubicin (daunomycin, daunomycinone).

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Bibliographic Details
Main Authors GAETANO ORSINI, JEROME BRETON, SILVIA FILIPPINI
Format Patent
LanguageEnglish
Published 24.02.1999
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPIRITS
VINEGAR
WINE
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Summary:5'-Methylthioadenosine nucleosidase is used as a cofactor for carminomycin 4-O-methyltransferase. The system may be used to convert carminomycin, especially when present as a contaminant in daunorubicin solution, into daunorubicin (daunomycin, daunomycinone).
Bibliography:Application Number: GB19950012895