COMPOSES CAPABLES DE MODULER L'ACTIVITE ET DE STIMULER LA PRODUCTION D'UN ANTICORPS CATALYTIQUE

The invention concerns novel compounds capable of modulating the activity and stimulating the production of catalytic antibodies. More particularly, the invention concerns a compound capable of increasing the activity of an antibody characterised in that it has specific affinity for the catalytic si...

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Bibliographic Details
Main Authors DEBAT HELENE, THOMAS DANIEL, FRIBOULET ALAIN, AVALLE BIHAN BERANGERE
Format Patent
LanguageFrench
Published 29.11.2002
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention concerns novel compounds capable of modulating the activity and stimulating the production of catalytic antibodies. More particularly, the invention concerns a compound capable of increasing the activity of an antibody characterised in that it has specific affinity for the catalytic site of said antibody, and it is not immunogenic. Such compounds are useful in particular for therapeutic treatment or prevention of a pathology related to an enzymatic deficiency, to stimulate in vivo hydrolysis of xenobiotics, drugs, medicines or any other molecule potentially toxic for the organism or for preventing or inhibiting allergic reactions. L'invention a trait à des nouveaux composés capables de moduler l'activité et de stimuler la production des anticorps catalytiques. L'invention porte en particulier sur un composé capable d'augmenter l'activité d'un anticorps catalytique caractérisé en ce qu'il a une affinité spécifique pour le site catalytique dudit anticorps, et en ce qu'il n'est pas immunogène. De tels composés sont utiles en particulier pour le traitement thérapeutique ou la prévention d'une pathologie liée à une déficience enzymatique, pour stimuler in vivo l'hydrolyse de xénobiotiques, de drogues, de médicaments ou toute autre molécule potentiellement toxique pour l'organisme ou encore pour prévenir ou empêcher des réactions allergiques.
Bibliography:Application Number: FR20010006754