QUINOLEINES SUBSTITUEES POUR LE TRAITEMENT DE CO-INFECTIONS A PROTOZOAIRES ET A RETROVIRUS

The invention relates to the use of quinolines having general formula (I), wherein R1 denotes H; alkyl C1-C15; alkenyl or alkynyl C2-C15; -CHO; heteroaryl; alkyl C1-C15 or alkenyl or alkynyl C2-C7 comprising at least one substituent selected from among O, halogen, -OH, -CHO, -COOH, aryloxycarbonyl,...

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Bibliographic Details
Main Authors FRANCK XAVIER, FAKHFAKH MOHAMED AKRAM, FIGADERE BRUNO, FOURNET ALAIN, HOCQUEMILLER REYNALD, PRINA ERIC
Format Patent
LanguageFrench
Published 28.09.2007
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to the use of quinolines having general formula (I), wherein R1 denotes H; alkyl C1-C15; alkenyl or alkynyl C2-C15; -CHO; heteroaryl; alkyl C1-C15 or alkenyl or alkynyl C2-C7 comprising at least one substituent selected from among O, halogen, -OH, -CHO, -COOH, aryloxycarbonyl, alkyloxycarbonyl C2-C8, alkenyloxycarbonyl C3-C9, nitrile, aryl, heteroaryl, arylsulphone, alkylsulphone C1-C7, thioalkyl or aminoalkyl C1-C7; alkenyl C2-C 7 bearing at least one substituent selected from among NH2, aleoxy C1-C7, phenoxy, cycloakyl C3-C6 or heteroaryloxy, alkenyl or alkynyl C2-C15 comprising at least one trialkylsilyl C1-C7; R2, in position 3, 6 or 8, denotes H; halogen; -OH; -CHO; -COOH; alkyl or aleoxy C1-C7; -NH2; alkenyl C2-C7; or alkynyl C2-C10; R1 and R2 do not both denote H. The invention is used for the preparation of a medicine to treat protozoan and retrovirus co-infections
Bibliography:Application Number: FR20010000580